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Sample Preparation Homogenizers

At Omni International, we are dedicated to providing cutting-edge laboratory equipment that empowers scientists and researchers worldwide.

Our extensive range of laboratory homogenizers is designed to meet your precise homogenization needs, ensuring reliable and efficient sample preparation for your experiments.

As a Leader In The Sample Preparation industry,

We offer a comprehensive selection of homogenizers, each tailored to specific applications and laboratory requirements. Whether you're working with biological samples, pharmaceutical formulations, food and beverage products, or any other sample type, we have the perfect homogenizer to streamline your workflow.

Homogenizers are versatile laboratory tools that play a crucial role in various scientific disciplines. These powerful instruments are designed to achieve uniformity and consistency in sample preparation by breaking down particles and emulsifying substances, releasing analytes of interest for downstream assays. Here are some common applications and uses of homogenizers:

Biological and Life Sciences

Homogenizers are widely utilized in biological and life science research for the extraction of proteins, DNA, RNA, and other cellular components. They aid in cell disruption, tissue homogenization, and the release of analytes, allowing researchers to study cellular processes, conduct genomic analysis, and explore bio-molecular interactions.

Pharmaceutical and Drug Development

In the pharmaceutical industry, homogenizers are an indispensable resource in formulating pharmaceutical compounds, as well as pushing forward cutting-edge drug development assays. They facilitate the blending of active pharmaceutical ingredients with excipients, ensuring uniform distribution and particle size reduction for lipid emulsion preparation, and encapsulation of drugs in nano-particle systems. Homogenizers also play a pivotal role in drug-development assays. By enabling a high-throughput and streamlined sample preparation workflow upstream of ADME and DMPK assays, the bottlenecks are eliminated allowing researchers to bring cutting-edge therapeutics to the pre-clinical and clinical markets.

Food and Beverage Processing

Homogenization is a key process in the food and beverage industry. Homogenizers help create stable emulsions, prevent separation, and improve product consistency. They are commonly used in dairy processing to achieve a smooth texture, prevent cream separation, and enhance product shelf life. Additionally, homogenizers aid in the production of sauces, dressings, juices, and other liquid-based food products.

Cosmetics and Personal Care Products

Homogenizers play a vital role in formulating cosmetic and personal care products, such as creams, lotions, and emulsions. They ensure the proper dispersion of ingredients, create stable emulsions, and allow for precise control of active ingredient addition. Using a homogenizer also helps to facilitate batch-to-batch consistency by use of programmable/semi-programmable functions.

Chemical and Industrial Applications

Homogenizers find applications in various chemical and industrial processes. They assist in particle size reduction, dispersion of pigments and additives in coatings and paints, preparation of stable emulsions for lubricants and fuels, and homogenization of suspensions and slurries. Homogenizers contribute to improved product quality, consistency, and efficiency in diverse industrial sectors.

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What homogenizer is best for me

What homogenizer is best for me

How to Choose the Right Homogenizer for Your Laboratory

How to Choose the Right Homogenizer for Your Laboratory


How to Select a Handheld Homogenizer

Omni Homogenizer Solutions

Bead Mill Homogenizers

Bead mill homogenizers, also known as bead beaters or bead mills, are laboratory instruments used for sample disruption, homogenization, and particle size reduction.

They are widely utilized in biological, chemical, pharmaceutical, and research laboratories for various applications. Discover the impact that homogenizers have in major industries here.

Here's what you need to know about bead mill homogenizers:

  • Principle of Operation

    Bead mill homogenizers work based on the principle of mechanical disruption. They utilize small grinding beads, typically made of materials like glass, zirconium oxide, or stainless steel, which are agitated at high speeds within a sample-containing tube or vial. The grinding beads collide with the sample, imparting mechanical forces that disrupt cells, break apart particles, and achieve homogenization.

  • Sample Disruption

    Bead mill homogenizers are highly effective in breaking down cells, tissues, and other sample materials. The high-speed agitation of the grinding beads generates intense shear forces and impacts, resulting in the disruption of cell walls, membranes, and structures. This allows for the release of intracellular components, DNA, RNA, proteins, and other biomolecules, enabling downstream applications and analysis.

  • Homogenization Efficiency

    Bead mill homogenizers offer excellent homogenization efficiency, particularly for tough or resistant samples. The mechanical disruption achieved by the grinding beads ensures thorough and uniform homogenization, leading to reliable and consistent results. Bead mills are known for their ability to handle difficult sample types, including tough tissues, microbial cultures, plant materials, and more.

  • Particle Size Reduction

    In addition to sample disruption, bead mill homogenizers can also reduce particle size. The grinding beads effectively grind and pulverize particles, leading to a narrower size distribution and finer particle sizes. This feature is beneficial for applications requiring consistent particle sizing or for achieving efficient extraction of target molecules.

  • Versatility

    Bead mill homogenizers are versatile instruments that can accommodate a wide range of sample types and volumes. They are used in various fields, including molecular biology, cell biology, microbiology, biotechnology, pharmaceuticals, and more. Bead mills are suitable for applications such as DNA/RNA extraction, protein analysis, cell lysis, sample preparation for PCR, immunoprecipitation, and particle size reduction.

  • Scalability

    Bead mill homogenizers are available in different sizes and capacities to meet diverse laboratory needs. They range from small benchtop units for low-volume processing to larger high-throughput systems for large-scale applications. This scalability allows researchers to choose the appropriate bead mill homogenizer based on their sample volume and processing requirements.

  • User-Friendly Features

    Bead mill homogenizers often feature user-friendly designs and interfaces. They come equipped with programmable settings for controlling parameters such as speed, time, and temperature. Many models offer built-in safety features to prevent sample contamination and instrument damage, ensuring reliable and safe operation.

Bead mill homogenizers' effectiveness stems from their ability to provide high shear forces, versatility in sample processing, scalability, reproducibility, and user-friendly operation. These features make them indispensable tools in laboratories involved in various research areas, including molecular biology, cell biology, biotechnology, and pharmaceutical development.

Omni's Bead Mill Solutions
Bead Mill Media

Rotor Stator | Handheld Homogenizers

Rotor-stator homogenizers, also known as high-speed homogenizers or rotor-stator generators, are commonly used laboratory instruments for sample homogenization, emulsification, dispersion, and particle size reduction. They utilize a rotor and stator assembly to generate high shear forces and mechanical agitation, resulting in efficient sample disruption and mixing.

Here's what you need to know about rotor-stator homogenizers:

  • Principle of Operation

    Rotor-stator homogenizers operate based on the principle of mechanical shear and turbulence. The rotor, typically a high-speed rotating shaft with blades or teeth, creates a shearing action as it passes through the stationary stator. This shearing action disrupts cells, breaks apart particles, and promotes mixing and emulsification.

  • Shear Forces and Mixing

    Rotor-stator homogenizers generate powerful shear forces, which effectively disrupt cells and particles, leading to homogenization and particle size reduction. The intense mechanical agitation and turbulence created by the rotor-stator assembly ensure thorough mixing and blending of sample components.

  • Adjustable Speed Settings

    Rotor-stator homogenizers typically offer adjustable speed settings, allowing users to optimize the homogenization process for different sample types and viscosities. Controlling the rotational speed of the rotor enables fine-tuning of the shear forces applied to the sample, ensuring efficient homogenization while maintaining sample integrity.

  • Interchangeable Generator Probes

    Rotor-stator homogenizers often come with a variety of interchangeable generator probes, including saw-tooth, toothed, and fine-toothed designs. These probes can be selected based on the application and sample characteristics. The choice of generator probe allows for precise control over the homogenization process and enhances the versatility of the instrument.

  • Reproducible Results

    Rotor-stator homogenizers deliver reproducible results, ensuring consistent sample homogenization across experiments. The controlled shear forces and optimized settings provided by these homogenizers allow for reliable and repeatable outcomes, minimizing variability and improving data quality.

  • Sample Volume Flexibility

    Rotor-stator homogenizers are available in various sizes, accommodating a wide range of sample volumes. They can handle small to large sample volumes, making them suitable for both research and industrial-scale applications. This flexibility allows researchers to homogenize samples of different sizes without the need for multiple instruments.

  • Ease of Use

    Rotor-stator homogenizers are designed for ease of use, featuring intuitive controls and ergonomic designs. They are typically compact, benchtop instruments that can be easily operated by scientists and technicians. Quick and straightforward setup and operation make rotor-stator homogenizers user-friendly and time-efficient.

Rotor-stator homogenizers are valued for their powerful homogenization capabilities, versatility, adjustable speed settings, interchangeable generator probes, reproducibility, sample volume flexibility, ease of use, and scalability. These features make rotor-stator homogenizers effective tools for achieving efficient and reliable sample homogenization in various scientific and industrial settings.

Omni's Rotor-Stator Solutions
Rotor-Stator Media

Automated Homogenizers

Automated homogenizers are advanced laboratory instruments designed to streamline and automate the homogenization process. They offer precise control, programmability, and convenience, making them highly efficient tools for sample preparation.

Here's what you need to know about automated homogenizers:

  • Automation and Programmability

    Automated homogenizers are equipped with advanced automation features, allowing for precise and reproducible sample processing. They typically feature programmable settings, including speed, time, and other parameters, enabling users to set specific homogenization protocols tailored to their samples and applications. This automation reduces user variability and ensures consistent results across experiments.

  • Motorized Probes

    Automated homogenizers often utilize motorized probes or heads that perform the homogenization process. These probes can be programmed to move in various patterns and directions within the sample, ensuring thorough and consistent disruption. Motorized probes offer precise control over the homogenization process, allowing for optimized sample preparation.

  • Multiple Sample Processing

    Automated homogenizers are capable of processing multiple samples simultaneously, increasing throughput and efficiency. They are equipped with sample holders or adapters that accommodate multiple tubes or plates, enabling high-throughput processing and reducing the overall processing time. This feature is especially advantageous in applications that require homogenization of numerous samples.

  • User-Friendly Interface

    Automated homogenizers typically feature user-friendly interfaces, making them accessible and easy to operate. They often have touchscreens or intuitive control panels that allow users to input settings, select programs, and monitor the progress of the homogenization process. The user-friendly interface simplifies operation and reduces the learning curve.

  • Reproducible Results

    Automated homogenizers deliver reproducible results, ensuring consistent sample preparation and homogenization across experiments. The automation and precise control offered by these instruments minimize user variability and eliminate manual errors, leading to reliable and repeatable outcomes. This is particularly important in applications that require accurate and consistent sample processing.

  • Versatility

    Automated homogenizers are versatile instruments suitable for a wide range of sample types and applications. They can handle various sample volumes, from small microtubes to larger containers, allowing flexibility in processing different sample sizes. Automated homogenizers can be used in fields such as molecular biology, microbiology, biotechnology, pharmaceuticals, and more.

  • Time and Labor Savings

    The automation provided by these homogenizers significantly reduces the time and effort required for sample preparation. Automated homogenizers allow researchers to allocate their time and resources more efficiently, freeing up personnel for other tasks and increasing overall productivity in the laboratory.

  • Integration with Workflows

    Automated homogenizers can be seamlessly integrated into existing laboratory workflows and robotic systems. They often have standardized interfaces or connectivity options that enable integration with robotic platforms or liquid handling systems, further enhancing automation and workflow efficiency.

Automated homogenizers combine advanced automation, programmability, and user-friendly interfaces to provide efficient and reproducible sample preparation. With their ability to handle multiple samples simultaneously and their versatility in processing various sample types, automated homogenizers are valuable tools in scientific research, quality control, and industrial applications.

Omni's Automated Solutions

Ultrasonic Homogenizers

Ultrasonic homogenizers, also known as ultrasonic disruptors or sonicators, are powerful laboratory instruments that utilize high-frequency sound waves to disrupt cells, break down particles, and emulsify samples. They are widely used in various scientific fields for sample preparation, dispersion, extraction, and other applications.

Here's what you need to know about bead mill homogenizers:

  • Principle of Operation

    Ultrasonic homogenizers work based on the principle of acoustic cavitation. They generate high-frequency sound waves (typically in the range of 20 kHz to several MHz) through a piezoelectric transducer. These sound waves create alternating high-pressure and low-pressure cycles in the sample, leading to the formation and collapse of tiny bubbles called cavitation bubbles. The implosion of these bubbles generates localized energy and shear forces, causing disruption and homogenization of the sample.

  • Sample Disruption and Homogenization

    Ultrasonic homogenizers are highly effective at disrupting cells and breaking down particles. The intense shear forces and microstreaming created by the collapse of cavitation bubbles result in the disruption of cell walls, membranes, and other structures, allowing for the release of intracellular components. Ultrasonic homogenizers achieve thorough sample homogenization, ensuring uniform distribution of particles, emulsification, and dissolution.

  • Non-Thermal Process

    Ultrasonic homogenization is a non-thermal process, meaning it does not involve significant heat generation. The energy released by cavitation bubbles is localized and transient, resulting in minimal sample heating. This makes ultrasonic homogenizers suitable for heat-sensitive samples, preserving the integrity of sensitive molecules and reducing the risk of denaturation or degradation.

  • Versatile Applications

    Ultrasonic homogenizers find applications in various scientific fields, including biology, chemistry, pharmaceuticals, nanotechnology, and more. They are used for cell disruption, DNA/RNA extraction, protein extraction, emulsification, dispersion of nanoparticles, degassing, sample preparation for analysis, and the formulation of stable emulsions.

  • Sample Volume Range

    Ultrasonic homogenizers can handle a wide range of sample volumes, from small microtubes to larger containers. They are available in different probe sizes and configurations to accommodate various sample volumes, providing flexibility in processing different sample sizes.

  • Adjustable Power and Amplitude

    Ultrasonic homogenizers typically offer adjustable power and amplitude settings. Users can control the intensity of the ultrasonic energy applied to the sample, allowing for optimization based on sample characteristics, viscosity, and desired outcomes. This flexibility enables fine-tuning of the homogenization process for different sample types and applications.

  • User-Friendly Operation

    Ultrasonic homogenizers are generally user-friendly instruments with intuitive controls and interfaces. They often feature digital displays, timers, and adjustable settings, making them easy to operate. The compact design and ergonomic features of ultrasonic homogenizers enhance user convenience and ensure efficient sample processing.

  • Reproducible Results

    Ultrasonic homogenizers deliver reproducible results, ensuring consistent sample preparation across experiments. The controlled energy and shear forces provided by these instruments enable reliable and repeatable outcomes, minimizing variability and improving the accuracy of scientific research and industrial processes.

Ultrasonic homogenizers offer non-thermal sample disruption, versatility in applications, adjustable settings, user-friendly operation, and reproducibility. These features make ultrasonic homogenizers valuable tools for sample preparation and homogenization in various scientific and industrial settings.

Omni's Ultrasonic Solutions
Ultrasonic Media
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